The core-inversible micelles for hydrophilic drug delivery

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The core-inversible micelles for hydrophilic drug delivery.

A unique core-inversible micelle (CIM) was formed via PEG(5k)CA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

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ژورنال

عنوان ژورنال: Chemical Communications

سال: 2013

ISSN: 1359-7345,1364-548X

DOI: 10.1039/c3cc43209b